I-Pepsin, i-enzyme enamandla kujusi yesisu egaya amaprotheni njengalawo asenyameni, amaqanda, imbewu, noma imikhiqizo yobisi.I-Pepsin iwuhlobo olusebenzayo oluvuthiwe lwe-zymogen (iphrotheni engasebenzi) i-pepsinogen.

I-Pepsinyaqala ukuqashelwa ngo-1836 yisazi se-physiologist saseJalimane uTheodor Schwann.Ngo-1929 i-crystallization yayo kanye nemvelo yamaprotheni kwabikwa yisazi samakhemikhali ezinto eziphilayo saseMelika uJohn Howard Northrop we-Rockefeller Institute for Medical Research.(Kamuva uNorthrop wathola isabelo soMklomelo KaNobel Wekhemistry wango-1946 ngomsebenzi wakhe wokuhlanza ngempumelelo kanye nokuhlanganisa ama-enzyme.)

Izindlala zolwelwesi lwamafinyila esiswini zenza futhi zigcine i-pepsinogen.Impulses kusukela i-vagus nerve kanye ne-hormone secretions ye-gastrin ne-secretin ikhuthaza ukukhululwa kwe-pepsinogen esiswini, lapho ixubene ne-hydrochloric acid futhi iguqulelwe ngokushesha ku-enzyme esebenzayo i-pepsin.Amandla okugaya e-pepsin makhulu ku-acidity yejusi yesisu evamile (pH 1.5-2.5).Emathunjini i-gastric acid iyancipha (pH 7), futhi i-pepsin ayisasebenzi.

Emgudwini wokugaya ukudla i-pepsin ithinta kuphela ukuwohloka okuncane kwamaprotheni abe amayunithi amancane abizwa ngokuthi ama-peptide, okuthi bese kuthintwa emathunjini aye egazini noma aphinde aphuke ngama-enzyme e-pancreatic.

Inani elincane le-pepsin lidlula lisuka esiswini liye egazini, lapho lihlephula khona izingcezu ezinkulu, noma ezingakagayeki kancane, okungenzeka ukuthi zimuncwe amathumbu amancane.

Ukubuyela emuva okungamahlalakhona kwe-pepsin, i-asidi, nezinye izinto ezisuka esiswini ziye emphinjeni kwakha isisekelo sezimo ze-reflux, ikakhulukazi isifo se-reflux ye-gastroesophageal kanye ne-laryngopharyngeal reflux (noma i-extraesophageal reflux).Ekugcineni, i-pepsin ne-asidi zihamba zize zifike emphinjeni, lapho zingabangela khona umonakalo ku-laryngeal mucosa futhi ziveze izimpawu ezisukela ekuhwebeni nokukhwehlela okungapheli kuya ku-laryngospasm (ukufinyela okungahleliwe kwezintambo zezwi) kanye nomdlavuza we-laryngeal.

I-Deebio'i-pepsinikhishwa ku-porcine gastric mucosa yekhwalithi ephezulu ngobuchwepheshe bethu bokukhipha okukhethekile.Isetshenziswa kabanzi ekwelapheni i-dyspepsia okubangelwa ukudla ngokweqile ukudla okune-protein.ukungasebenzi kahle kokugaya ukudla ngesikhathi sokululama kanye nokuntuleka kwe-proteinase yesisu okubangelwa i-atrophic gastritis engapheli, umdlavuza wesisu kanye ne-anemia eyingozi.

Njengoba kuze kube yiminyaka engu-30 yocwaningo lwesayensi nomkhuba wezimboni, sesisungule “i-DEEBIO 3H Technology” eyingqayizivele, sisebenzisa yonke inqubo yokuvikela i-enzymatic. Ubuchwepheshe bokulawula obuyinhloko, ngokuvula okungabhubhisi, kuvusa i-zymogen, futhi siqaphele umsebenzi ophezulu, ukuhlanzeka okuphezulu nokuzinza okuphezulu kwemikhiqizo ye-bio-enzyme.

Siyakwamukela ukuxhumana nathi, sibheke ngabomvu ukuxhumana nawe futhi silindele ngobuqotho uphenyo lwakho